Ehlers-Danlos Syndrome Genetic Test
£1,375
- Results: 6 weeks
- Genetic counselling recommended
- Walk-in available 7 days
UKAS LAB · HARLEY STREET
Ehlers-Danlos Syndrome Genetic Test
If you've spent years seeking answers for hypermobile joints, fragile skin, chronic pain, or unexplained injuries, genetic testing can confirm whether Ehlers-Danlos syndrome is the cause.
Results6 weeks
Time20-30m
Price£1,375
AvailabilityWalk-in available 7 days
Est. 1984
Trusted clinical caresince 1984
UKAS-accredited labsGP & consultant pathways
As Featured In
Ehlers-Danlos syndrome genetic test in London
The Ehlers-Danlos syndrome genetic test at Medical Express Clinic is a next-generation sequencing (NGS) panel for gene variants associated with Ehlers-Danlos syndrome (EDS), a group of inherited connective tissue disorders affecting the skin, joints and blood vessels.
EDS is often suspected when someone has unusually flexible joints, stretchy or fragile skin, and a history of joint dislocations or chronic pain.
The EDS genetic panel covers genes linked to Classical EDS (COL5A1, COL5A2), Vascular EDS (COL3A1), and kyphoscoliotic, arthrochalasia and other rare subtypes.
A genetic diagnosis can confirm which type of EDS is present and guide medical management, but hypermobile EDS is primarily a clinical diagnosis, so the EDS genetic panel helps exclude other types rather than confirm the hypermobile type.
The EDS genetic test suits adults or children with suspected EDS, family members of someone with a confirmed diagnosis, and patients referred by rheumatology, genetics or pain specialists.
The Ehlers-Danlos syndrome genetic test costs £1,375, results take 6 weeks, and genetic counselling is recommended before and after testing.
The EDS genetic test can be booked online or arranged on a walk-in basis 7 days a week at 117a Harley Street, London.
How much does an EDS genetic test cost in London?
An Ehlers-Danlos syndrome genetic test costs £1,375 at Medical Express Clinic, with results in 6 weeks, and genetic counselling is recommended and can be arranged by referral.
The panel screens for genes associated with:
- • Classical EDS (COL5A1, COL5A2)
- • Vascular EDS (COL3A1) - the most serious form requiring specific surveillance
- • Kyphoscoliotic, arthrochalasia, and other rare subtypes
- • Hypermobile EDS - primarily a clinical diagnosis; genetic testing helps exclude other types
Who should consider this test:
- • Adults or children with suspected EDS based on clinical features
- • Family members of someone with a confirmed EDS diagnosis
- • Those seeking confirmation after years of unexplained symptoms
- • Patients referred by rheumatology, genetics, or pain specialists
Why test at Medical Express Clinic: We work with UKAS-accredited genetics laboratories. Genetic counselling is recommended before and after testing. A positive result can inform treatment, surveillance for complications (particularly with vascular EDS), and family planning decisions.
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Clinical lead
Dr Penny Sheehan
Health Screening, Paediatrics and Menopause • GMC 6056535
“Dr Sheehan works in women's health, menopause care and health screening. She has training and experience in weight management, including GLP-1 receptor agonist prescribing, and a special interest in paediatric assessment.”
Service information reviewed 26 August 2026.
FAQs
EDS genetic test FAQs
What if the test is negative but I still have symptoms?
Hypermobile EDS, the most common type, is diagnosed clinically rather than genetically. A negative genetic test doesn't exclude EDS; it helps rule out rarer forms.
Is genetic counselling included?
We recommend genetic counselling and can refer you. This is particularly important for understanding implications for family members.
Can I claim this on insurance?
Some insurers cover genetic testing with a referral letter. We can provide documentation to support your claim.
