Lupus Anticoagulant Test
Recurrent miscarriage. Unexplained blood clots. A clotting test that came back "prolonged" without explanation. Lupus anticoagulant antibodies may be the missing piece.
Est. 1984
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The Lupus Anticoagulant test detects antibodies that interfere with normal blood clotting. Despite its name, this test is not specifically for lupus. It identifies a clotting abnormality that increases the risk of blood clots, stroke, and pregnancy complications.
Lupus anticoagulant is one of the antiphospholipid antibodies. When present, these antibodies make blood more likely to clot inappropriately in veins and arteries. This is particularly significant during pregnancy, where it can contribute to recurrent miscarriage or placental problems.
This test is commonly requested for:
- • Recurrent miscarriage (two or more pregnancy losses)
- • Unexplained blood clots, especially at a young age
- • Stroke or TIA without obvious cause
- • Prolonged aPTT on routine blood tests
- • Assessment for antiphospholipid syndrome (APS)
A positive result usually requires confirmation with a repeat test 12 weeks later, as transient positives can occur after infections.
More comprehensive option:
For a fuller assessment, the Hughes Syndrome profile (£151.25) includes lupus anticoagulant plus anticardiolipin antibodies, covering more of the antiphospholipid antibody spectrum.
Book Hughes Syndrome Test →Book your Lupus Anticoagulant Test - results in 2 days
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Specialist & genetic
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Dr Penelope Sheehan
Health Screening, Paediatrics and Menopause • GMC 6056535
“Dr Sheehan works in women's health, menopause care and health screening. She has training and experience in weight management, including GLP-1 receptor agonist prescribing, and a special interest in paediatric assessment.”
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Common questions
Q.Why is it called "anticoagulant" if it causes clots?
Confusingly, lupus anticoagulant prolongs clotting times in the test tube but causes excessive clotting in the body. The name refers to the lab finding, not the clinical effect.
Q.I've had one miscarriage. Should I test?
Testing is typically recommended after two or more losses, but your doctor may suggest it earlier depending on other factors.
Q.Why might a positive lupus anticoagulant result need confirmation?
A positive result usually requires confirmation with a repeat test 12 weeks later, as transient positives can occur after infections.
