Hughes Syndrome Blood Test
Recurrent miscarriages. Blood clots without explanation. A stroke in your 30s or 40s. If you've been searching for answers and coming up empty, Hughes Syndrome may be the diagnosis that changes everything.
Hughes Syndrome, also called antiphospholipid syndrome (APS), is an autoimmune condition where your immune system produces antibodies that make blood clot too easily. It's one of the most common causes of recurrent pregnancy loss and unexplained clots in younger adults, yet many people go years without diagnosis.
This test screens for:
- • Lupus anticoagulant
- • Anticardiolipin antibodies (IgG and IgM)
Testing is appropriate if you have experienced:
- • Two or more unexplained miscarriages
- • Blood clots (DVT or PE) without clear cause
- • Stroke or TIA, especially under age 50
- • Livedo reticularis (mottled skin pattern)
- • Migraines with visual disturbance
A positive result requires confirmation with repeat testing after 12 weeks to distinguish persistent antibodies from temporary elevations caused by infection.
The good news: Once diagnosed, Hughes Syndrome is treatable. Anticoagulation therapy significantly reduces the risk of further clots and pregnancy loss. Many women with Hughes Syndrome go on to have successful pregnancies with appropriate treatment.
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Hughes Syndrome Blood Test
£151.25Related blood tests
Common questions
Q.Why haven't I been tested before?
Hughes Syndrome is underdiagnosed because symptoms mimic other conditions. Many patients are only tested after multiple events. You don't need a referral to test privately.
Q.What happens if my test is positive?
Our GP will review your result and discuss the need for confirmatory testing in 12 weeks. If confirmed, referral to a rheumatologist or haematologist for management is typically recommended.
Q.Can Hughes Syndrome be cured?
It's managed rather than cured. With appropriate treatment (usually blood-thinning medication), most people live normal lives with significantly reduced risk of complications.