Sjögren's Syndrome Blood Test
Dry eyes that drops don't fix. A dry mouth that makes eating difficult. Fatigue that people dismiss as stress. If you've been told nothing is wrong but you know something is, Sjögren's syndrome may be the answer.
Sjögren's syndrome is an autoimmune condition where the immune system attacks moisture-producing glands. The result is persistent dry eyes, dry mouth, and fatigue that significantly affects quality of life. This blood test screens for the antibodies associated with the condition.
The test includes:
- • Anti-SSA (Ro) antibodies
- • Anti-SSB (La) antibodies
- • ANA (antinuclear antibodies)
- • Rheumatoid factor
Anti-SSA and Anti-SSB are the most specific markers for Sjögren's. Around 70% of people with primary Sjögren's have one or both antibodies present.
Symptoms that suggest Sjögren's syndrome:
- • Persistent dry eyes (gritty sensation, redness, sensitivity to light)
- • Dry mouth affecting eating, speaking, and dental health
- • Joint pain and fatigue
- • Vaginal dryness
- • Dry skin or skin rashes
Sjögren's can occur alone (primary) or alongside other autoimmune conditions like rheumatoid arthritis or lupus (secondary). Diagnosis often takes years because the symptoms overlap with many other conditions.
A note on negative results: Around 30% of people with Sjögren's are "seronegative," meaning they have the condition without detectable antibodies. If your results are negative but symptoms persist, further investigation (such as a lip biopsy) may be warranted.
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Sjögren's Syndrome Blood Test
£137.50Common Questions
Q.Why does it take 15 days for results?
The specialised antibody tests require time for laboratory processing. We'll contact you as soon as results are available.
Q.What happens if the test is positive?
Our GP will discuss findings and can refer you to rheumatology for confirmation and management planning.
Q.Is Sjögren's syndrome treatable?
While there's no cure, treatments can significantly improve symptoms. These include artificial tears, saliva substitutes, and medications to reduce immune system activity.
