Sjögren's Syndrome Blood Test
£137.50
- Results: 15 working days
- Laboratory report; GP consultation £150 extra
- Walk-in available 7 days
UKAS LAB · HARLEY STREET
Sjögren's Syndrome Blood Test
Dry eyes that drops don't fix. A dry mouth that makes eating difficult. Fatigue that people dismiss as stress. If you've been told nothing is wrong but you know something is, Sjögren's syndrome may be the answer.
Results15 working days
Time20-30m
Price£137.50
AvailabilityWalk-in available 7 days
Est. 1984
Trusted clinical caresince 1984
UKAS-accredited labsGP & consultant pathways
As Featured In
Sjögren's syndrome blood test in London
The Sjögren's syndrome blood test at Medical Express Clinic screens for antibodies associated with Sjögren's syndrome, an autoimmune condition affecting the moisture-producing glands.
The Sjögren's syndrome test includes anti-SSA (Ro) and anti-SSB (La) antibodies, ANA (antinuclear antibodies) and rheumatoid factor.
Anti-SSA and anti-SSB are the most specific markers for Sjögren's syndrome, and around 70% of people with primary Sjögren's have one or both antibodies present.
The Sjögren's syndrome test is often requested for persistent dry eyes, dry mouth, joint pain and fatigue.
The Sjögren's syndrome blood test costs £137.50, with a GP consultation £150 extra, and results take 15 working days.
Some people with Sjögren's syndrome have no detectable antibodies, so a negative result with ongoing symptoms may need further investigation.
The Sjögren's syndrome test can be booked online or arranged on a walk-in basis 7 days a week at 117a Harley Street, London.
How much does a Sjögren's syndrome test cost in London?
A Sjögren's syndrome blood test costs £137.50 at Medical Express Clinic, covering anti-SSA (Ro), anti-SSB (La), ANA and rheumatoid factor, with results in 15 working days; a GP consultation is £150 extra.
Symptoms that suggest Sjögren's syndrome:
- • Persistent dry eyes (gritty sensation, redness, sensitivity to light)
- • Dry mouth affecting eating, speaking, and dental health
- • Joint pain and fatigue
- • Vaginal dryness
- • Dry skin or skin rashes
Sjögren's can occur alone (primary) or alongside other autoimmune conditions like rheumatoid arthritis or lupus (secondary). Diagnosis often takes years because the symptoms overlap with many other conditions.
A note on negative results: Around 30% of people with Sjögren's are "seronegative," meaning they have the condition without detectable antibodies. If your results are negative but symptoms persist, further investigation (such as a lip biopsy) may be warranted.
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Clinical lead
Dr Penny Sheehan
Health Screening, Paediatrics and Menopause • GMC 6056535
“Dr Sheehan works in women's health, menopause care and health screening. She has training and experience in weight management, including GLP-1 receptor agonist prescribing, and a special interest in paediatric assessment.”
Service information reviewed 26 August 2026.
FAQs
Sjögren's syndrome test FAQs
Why does it take 15 days for results?
The specialised antibody tests require time for laboratory processing. We'll contact you as soon as results are available.
What happens if the test is positive?
Our GP will discuss findings and can refer you to rheumatology for confirmation and management planning.
Is Sjögren's syndrome treatable?
While there's no cure, treatments can significantly improve symptoms. These include artificial tears, saliva substitutes, and medications to reduce immune system activity.
