BRCA Gene Testing
BRCA1 and BRCA2 genetic testing to assess your hereditary risk of breast and ovarian cancer. Our Harley Street clinic offers expert genetic counselling alongside comprehensive testing.
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Understanding BRCA Gene Testing
BRCA1 and BRCA2 are genes that produce proteins responsible for repairing damaged DNA. When these genes have certain mutations, they can significantly increase the risk of developing breast cancer, ovarian cancer, and other related cancers.
Genetic testing for BRCA mutations can help you understand your personal risk and make informed decisions about preventive care, screening frequency, and treatment options.
Who Should Consider BRCA Testing?
Family History Indicators
- •Multiple relatives with breast or ovarian cancer
- •Breast cancer diagnosed before age 50
- •Male relative with breast cancer
- •Known BRCA mutation in the family
Personal History Factors
- •Triple-negative breast cancer diagnosis
- •Bilateral breast cancer
- •Ashkenazi Jewish ancestry
- •Previous ovarian cancer diagnosis
The Testing Process
Genetic Counselling
A pre-test consultation to discuss your family history, understand the implications of testing, and address any concerns you may have.
Blood Sample
A simple blood draw at our clinic. The sample is sent to an accredited genetic laboratory for comprehensive BRCA1 and BRCA2 analysis.
Results & Support
Results are typically available within 2-3 weeks. A follow-up consultation explains your results and outlines recommended next steps.
Understanding Your Risk
BRCA1 Mutation
Carries approximately 55-70% lifetime risk of breast cancer and 39-46% risk of ovarian cancer by age 70.
BRCA2 Mutation
Carries approximately 45-70% lifetime risk of breast cancer and 10-27% risk of ovarian cancer by age 70.
Note: Having a BRCA mutation does not mean you will develop cancer. Risk-reducing strategies and enhanced surveillance can significantly improve outcomes.
Risk Management Options
If you test positive for a BRCA mutation, several risk-reducing options are available:
- Enhanced Surveillance: More frequent mammograms, breast MRI scans, and clinical examinations.
- Chemoprevention: Medications that can reduce cancer risk in high-risk individuals.
- Risk-Reducing Surgery: Prophylactic mastectomy or oophorectomy for those who choose surgical prevention.
- Lifestyle Modifications: Evidence-based recommendations for exercise, diet, and alcohol consumption.
Our team will guide you through all available options and support you in making decisions that are right for you.
Treatment Menu & Fees
Transparent pricing for all our services.
BRCA1 & BRCA2 Full Panel
From £950Targeted BRCA Test
From £495Common Questions
Q.How long do BRCA test results take?
Results are typically available within 2-3 weeks. We will contact you to arrange a results consultation as soon as they are ready.
Q.Is genetic counselling included?
Yes, pre-test and post-test genetic counselling is included in the cost of the full panel test to ensure you fully understand the implications of testing.
Q.Can men have BRCA testing?
Yes. Men can carry BRCA mutations and pass them to children. Male BRCA carriers have increased risk of prostate cancer and male breast cancer.
Q.What happens if I test positive?
A positive result means you carry a mutation. We will discuss all risk management options including enhanced screening, preventive medications, and surgical options if appropriate.
